EXCITING NEWS!
We’ve Acquired BioEcho Life Sciences! Explore Innovative Nucleic Acid Extraction Solutions:
Epigenomics
Use NGS to probe modifications and regulations of the genome
NGS Epigenomic Services
ChIP-Seq
Use Chromatin Immunoprecipitation Sequencing (ChIP-seq) to gain intricate knowledge on regulators and explore targeted therapy development.
Scalable high throughput capability operating in CLIA-lab
Mature bioinformatics pipelines
Reduced bias with KAPA Hyper Prep
NEBNext® EM-seq™
EM-seq (Enzymatic Methyl-seq) is an enzyme-based method for methylome analysis that is less damaging to the DNA vs. bisulfite chemical approaches (WGBS/RRBS), using a two-step enzymatic conversion process to identify both 5mC & 5hmC sites.
Superior sequencing metrics vs. WGBS: higher library yields with fewer PCR cycles, larger library insert sizes, & lower percent duplication
Detects more CpGs with less reads, less GC bias, & more even coverage
CUT&RUN
Study epigenetic regulation and analyze the protein interactions with DNA. This technology isolates protein-DNA complexes of interest and can handle a low number of cells to reduce non-specific signals in data.
Optimized protocol for higher-resolution data
Quick turnaround
Scalable high throughput capability on Illumina platforms
WGBS
Genome-wide profiling of DNA methylation sites provides insight into epigenomic mapping, patterns of epigenetic markers, aberrant methylation, and more.
Optimized workflow for varying sample input
Superior data quality
Expert technical and bioinformatic support including QC, Mapping, Duplicate Removal, CpG and Non-CpG Differential Methylation Analysis, and more
ATAC-Seq
Genome-wide landscaping with Assay for Transposase-Accessible Chromatin sequencing (ATAC-seq) using a small starting input.
Reliable technical support for successful outcomes
Mature bioinformatic pipeline and continuous support after project completion
RRBS
RRBS is an alternative method to studying methylated sites which utilize restriction enzymes unaffected by methylation.
Optimized workflow for varying sample input
Reduced cost compared to that of WGBS
Expert technical and project management support
Bioinformatic support including QC, Mapping, Duplicate Removal, CpG and Non-CpG Differential Methylation Analysis.
Hi-C Assay
High Throughput Chromosome Conformation Capture (Hi-C) Assay studies chromosomal interactions. Hi-C can identify genome-wide unbiased long-range interactions, and reveal chromosomal interactions.
Stringent QC steps to reduce non-specific interchromosomal contacts, improve on-target capture
Expert technical, project management, and bioinformatic support
Advantages of Working with Admera Health
Expert Scientific Support
Experienced technical support team with a solution-oriented mindset
High-Throughput Capabilities
Robust workflows to support high volume and high data throughput
High Data Quality
Improved workflows and quality steps to ensure superior data quality
