Sequencing at single-cell resolution to unlock cellular heterogeneity and function

Single-Cell Sequencing


What is Single-Cell Sequencing?

Single-cell sequencing has revolutionized our understanding of cellular heterogeneity by enabling the measurement of DNA, RNA, and proteins at the individual cell level. This powerful approach has unveiled a level of biological complexity previously unattainable. Single-cell RNA-seq (scRNA-seq) has been instrumental in identifying novel cell types, dissecting intricate gene regulatory networks, and illuminating key processes involved in cell development, differentiation, and responses to environmental cues. To address this, single-cell multiomic technologies integrate multiple data types within a single assay. This integrated analysis provides a more comprehensive view of cell identity and function, revealing the interplay between different molecular layers within individual cells. 

Single Cell Sequencing Applications

single cell sequencing in neuroscience

In-depth investigation of neuronal diversity to deepen understanding of brain circuitry & neorogenerative diseases

Neuroscience

single cell sequencing in identifying drug targets

Identify Drug Targets

Explore single-cell transcriptomes for identification of novel and emerging drug targets

single cell sequencing in biomarker discovery

Biomarker Discovery

Discover new cell populations for potential biomarkers & complex cell-to-cell interactions

single cell sequencing in cancer research

Reveal rare cell populations, resistance mechanisms, and intricate cellular interactions that drive cancer progression and inform development of targeted therapies

Cancer Research

single cell CRISPR screening
  • Immunology

  • Single-Cell CRISPR Screening

& Beyond!

Our Suite of Services

Single-Cell RNA Sequencing
(scRNA-seq)

Uncover whole transcriptome insights into cellular heterogeneity, gene expression, novel targets, and biomarkers from thousands of
single cells

Single-Cell Mutliome
ATAC + Gene Expression

Explore gene expression and chromatin accessibility simultaneously, to discover complex gene regulatory mechanisms and characterize novel cell types

Single-Cell Gene Expression
(Fixed samples)

Fix, batch, and run samples later for unsurpassed workflow flexibility and affordability to reveal crucial insights at the single-cell level from challenging sample types, like FFPE

Single-Cell
Immune Profiling

A multiomic solution to simultaneously analyze cell surface protein expression, antigen specificity, and CRISPR edits with 5’ gene expression

Single-Cell DNA Sequencing
(scDNA-seq)

Uncover whole genome insights at the single-cell level, revealing copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) for high-throughput scDNA-seq

Single-Cell ATAC-seq

Gain insight into chromatin accessibility from a single nucleus revealing protein interactions and transcription factors at the single-cell resolution

Single-Cell
CRISPR Screening

Gather scalable, in-depth readouts of specific CRISPR-driven gene edits or knockouts to investigate the intricate biology of gene function, development, disease status, and therapeutic responses of individual cells

Sample Prep &
Treatment Options

  • Dead cell removals

  • Single-nuclei options

  • Optimized workflows for different sample types

  • Pilot studies available

10x Genomics Certified Service Provider single cell

Trusted Providers & Certified Services with Our Lab

Dive Into Single-Cell Insights with our Suite of 10x Genomics Solutions

Technology from 10x deliver diverse solutions to support high-throughput, whole transcriptome single-cell analysis. Explore our suite of single-cell solutions as a 10x Genomics Certified Service Provider.

Our Certified Lab provides a suite of 10x Single-Cell Solutions:

  • Single-Cell Gene Expression (3’ GEX)

  • Single-Cell Immune Profiling (5’ VDJ, ADT)

  • Single-Cell ATAC

  • Single-Cell Multiome ATAC+GEX

  • Single-Cell Gene Expression FLEX (FFPE)

Parse Biosciences Certified Service Provider

Scalable Single-Cell Solutions

Admera Health is a Certified Service Provider for Parse Biosciences Evercode Whole Transcriptome technologies. The combinatorial barcoding technology uniquely tags mRNA within a cell & enables scalable solutions for diverse single-cell projects.

Evercode WT Mini: up to 10K-100K cells for 1-12 samples

Evercode WT: 10K-100K cells for 1-48 samples

Evercode WT Mega: 100K- 1M cells for 1-96 samples

Takara bio certified service provider

Whole Transcriptome & Whole Genome
Single-Cell Services

Admera Health is a Certified Service Provider for the Takara Shasta Single-Cell system. Explore flexible solutions for whole transcriptome and whole genome single-cell analysis:

SMART-seq Pro: High-sensitivity solution captures mRNA for deep sequencing and low-throughput studies

Shasta Total RNA-seq: Flexible, high-throughput & high-sensitivity assay enables researchers to gain insights into splicing isoforms, gene fusions, and SNPs

Whole Genome Amplification: High-throughput, unbiased whole genome amplification scDNA-seq solution to uncover CNVs and SNVs

singleron biotechnologies certified service provider single cell

Full-length BCR/TCR Immune Profiling

Admera Health is a Certified Service Provider for Singleron Biotechnologies. Explore single-cell RNA-seq, immune profiling, and single nucleus sequencing options for complete single-cell analysis:

sCircle: Full-length immune repertoire profiling

GEXSCOPE:

  • single-cell RNA-seq

  • single nucleus-seq

  • VDJ

Understanding Single-Cell Technologies & Their Features

scRNA-seq In Action

Admera Health provides comprehensive support for all projects, and delivers publication-ready data. Discover how researchers are using single-cell solutions at Admera Health to advance their studies.

See our single—cell sample submission guideline for sample preparation, packing, and shipping instructions.

Sending samples?

Get the Most Out of Your Study

Maximize your project’s potential with advanced single-cell data analysis solutions. Our team of expert bioinformaticians curate pipelines tailored to your project’s experimental design.

Advantages of Working with Admera Health

Industry Leading
Turnaround Time

Admera Health operates with urgency to deliver data while maintaining industry-leading quality

Expert Scientific Support

Knowledgeable service and support from experienced scientists

High Data Quality

Stringent quality control steps ensure high-quality data delivered for your research

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