High-Throughput Gene Expression
Admera Health provides comprehensive high-throughput gene expression screening to advance large-scale projects
High-Throughput Gene Expression Using RNA-seq
RNA sequencing (RNA-seq) is a transformative method for exploring the effects of drug treatments on gene expression across the entire transcriptome and allows researchers to gain comprehensive insights into cellular responses. However, conventional RNA-seq assays can present challenges relating to cost-effectiveness and labor requirements, particularly when analyzing large numbers of samples. Several platforms leverage RNA barcoding and multiplexed RNA-seq to provide rapid, cost-effective, and high-throughput transcriptome analysis, significantly enhancing the statistical power of differential gene expression studies.
These low-cost, scalable for high-throughput screening (HTS) and automation compatible approaches can drastically accelerate transcriptome research for drug discovery and other large-scale comparative studies.
High-Throughput Gene Expression Screening Applications
Gene expression profiling
Compound screening
Disease modeling
Functional Genomics
Personalized medicine
Drug discovery mechanism
of action
Complete Solutions For Your Research
Sequencing Services Built For High-Throughput Screening
Admera Health provides high-throughput RNA-seq solutions to accelerate discovery with quick turnaround times, superior data quality, and expertise from our team of PhD-level scientists from sample extraction through data interpretation.
High-Throughput Gene Expression Screening Capabilities
Flexible starting requirements: Cells or RNA from low starting input material
Rapid turnaround time: Data delivery within 10 business days
Advanced multiplexing: Increased multiplexing capabilities result in lower sequencing costs
Cutting-edge technology: 3’ Tag-seq technology results in high-throughput data with fewer sequencing reads at reduced costs
Our Optimized Workflow
Our workflow is designed to accommodate various techniques, including Smart-seq 3', QuantSeq Pool, DRUG-Seq, and BRB-Seq. The process begins with sample barcoding in plate format to enable multiplexing followed by sample pooling. Pooled samples undergo library preparation and sequencing followed by data analysis to extract valuable insights into gene expression patterns.
Solutions to Suit Your Project’s Scale
Comparison table of various high-throughput RNA-seq platforms and features for each workflow. Key features include input type, input range per well, and maximum sample pooling capabilities.
*For highly expressed gene while deep sequencing enables detection of low-abundance transcripts.
Get the Most out of Your High-Throughput Gene Expression Project
Maximize your project’s potential with advanced data analysis solutions for high-quality sequencing data. Our team of expert bioinformaticians curate pipelines tailored to your project’s experimental design.
See our sample submission guideline for sample preparation, packing, and shipping instructions.
